Inflammatory breast cancer: Activation of the aryl hydrocarbon receptor and its target CYP1B1 correlates closely with Wnt5a/b-β-catenin signalling, the stem cell phenotype and disease progression

The aim of the present study was to evaluate the expression levels of the aryl hydrocarbon receptor (AHR) and its target gene CYP1B1 and to correlate their expression with Wnt5a/b-β-catenin, the CD44+/CD24(−/low) cancer stem cell (CSC) subset and factors associated with poor prognosis in inflammator...

Full description

Bibliographic Details
Main Authors: Hossam T. Mohamed, Ramy Gadalla, Noura El-Husseiny, Hebatallah Hassan, Zhongyan Wang, Sherif A. Ibrahim, Mohamed El-Shinawi, David H. Sherr, Mona M. Mohamed
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Journal of Advanced Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123218301255