Break-induced replication is highly inaccurate.
DNA must be synthesized for purposes of genome duplication and DNA repair. While the former is a highly accurate process, short-patch synthesis associated with repair of DNA damage is often error-prone. Break-induced replication (BIR) is a unique cellular process that mimics normal DNA replication i...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-02-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC3039667?pdf=render |