GNAS and KRAS mutations are common in intraductal papillary neoplasms of the bile duct.

Intraductal papillary neoplasms of the bile duct (IPNB) shows favorable prognosis and is regarded as a biliary counterpart of intraductal papillary mucinous neoplasm (IPMN) of the pancreas. Although activating point mutations of GNAS at codon 201 have been detected in approximately two thirds of IPM...

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Bibliographic Details
Main Authors: Motoko Sasaki, Takashi Matsubara, Takeo Nitta, Yasunori Sato, Yasuni Nakanuma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3847161?pdf=render