Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways.

The ability of the pathogenic yeast Candida albicans to interconvert between budded and hyphal growth states, herein termed the budded-to-hyphal transition (BHT), is important for C. albicans development and virulence. The BHT is under the control of multiple cell signaling pathways that respond to...

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Bibliographic Details
Main Authors: John Midkiff, Nathan Borochoff-Porte, Dylan White, Douglas I Johnson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21966518/?tool=EBI