Vicinal difunctionalization of carbon–carbon double bond for the platform synthesis of trifluoroalkyl amines

Metal-free olefin diamination may display challenges, especially when targeting fluorinated amines. Here, the authors report a double nucleophilic functionalization of an activated alkene originated from a trifluoropropenyliodonium salt with two nucleophiles for the selective synthesis of trifluorom...

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Bibliographic Details
Main Authors: Ferenc Béke, Ádám Mészáros, Ágnes Tóth, Bence Béla Botlik, Zoltán Novák
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19748-z