Evaluation of the Effects of Human Beta-Interferon Scaffold Attachment Region (IFN-SAR) on Expression of Vascular Endothelial Growth Factor-Fc (VEGF-Fc) Fusion Protein Expression in Chinese Hamster Ovary (CHO) Cells

Evaluation of the Effects of Human Beta-Interferon Scaffold Attachment Region (IFN-SAR) on Expression of Vascular Endothelial Growth Factor-Fc (VEGF-Fc) Fusion Protein Expression in Chinese Hamster Ovary (CHO) Cells

Background: Recombinant anti-vascular endothelial growth factor (VEGF) monoclonal antibodies and Fc-fusion proteins have been widely used for the effective treatment of retinal neovascular diseases. In this regard, VEGFR-Fc fusions, which act as strong VEGF inhibitors, have been approved for the tre...

Full description

Bibliographic Details
Main Authors: Ehsan Naghneh, Es'hagh Pourmaleki, Azam Rahimpour
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2020-12-01
Series:Pharmaceutical Sciences
Subjects:
chinese hamster ovary cells
fusion protein
scaffold/matrix attachment region
vascular endothelial growth factor receptor
Online Access:https://ps.tbzmed.ac.ir/PDF/ps-26-393.pdf

Internet

https://ps.tbzmed.ac.ir/PDF/ps-26-393.pdf

Similar Items