Two CRISPR/Cas9-mediated methods for targeting complex insertions, deletions, or replacements in mouse

Two CRISPR/Cas9-mediated methods for targeting complex insertions, deletions, or replacements in mouse

Genetically modified model organisms are valuable tools for probing gene function, dissecting complex signaling networks, studying human disease, and more. CRISPR/Cas9 technology has significantly democratized and reduced the time and cost of generating genetically modified models to the point that...

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Bibliographic Details
Main Authors: Kyriel M. Pineault, Ana Novoa, Anastasiia Lozovska, Deneen M. Wellik, Moises Mallo
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:MethodsX
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016119302249

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http://www.sciencedirect.com/science/article/pii/S2215016119302249

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