Resveratrol improves survival, hemodynamics and energetics in a rat model of hypertension leading to heart failure.

Heart failure (HF) is characterized by contractile dysfunction associated with altered energy metabolism. This study was aimed at determining whether resveratrol, a polyphenol known to activate energy metabolism, could be beneficial as a metabolic therapy of HF. Survival, ventricular and vascular fu...

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Bibliographic Details
Main Authors: Stéphanie Rimbaud, Matthieu Ruiz, Jérôme Piquereau, Philippe Mateo, Dominique Fortin, Vladimir Veksler, Anne Garnier, Renée Ventura-Clapier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22028869/?tool=EBI