Cell division orientation is coupled to cell–cell adhesion by the E-cadherin/LGN complex

Cell–cell adhesion and oriented cell division play key roles in tissue architecture, but how they are coordinated is not known. Here, the authors show that E-cadherin interacts with LGN, and thereby provides a cortical cue that serves to stabilize cortical attachment of astral microtubules at cell–c...

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Bibliographic Details
Main Authors: Martijn Gloerich, Julie M. Bianchini, Kathleen A. Siemers, Daniel J. Cohen, W. James Nelson
Format: Article
Language:English
Published: Nature Publishing Group 2017-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13996