Cathepsin G-dependent modulation of platelet thrombus formation in vivo by blood neutrophils.

Neutrophils are consistently associated with arterial thrombotic morbidity in human clinical studies but the causal basis for this association is unclear. We tested the hypothesis that neutrophils modulate platelet activation and thrombus formation in vivo in a cathepsin G-dependent manner. Neutroph...

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Bibliographic Details
Main Authors: Nauder Faraday, Kathryn Schunke, Sofiyan Saleem, Juan Fu, Bing Wang, Jian Zhang, Craig Morrell, Sylvain Dore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3733958?pdf=render