Resveratrol Improves Brain-Gut Axis by Regulation of 5-HT-Dependent Signaling in the Rat Model of Irritable Bowel Syndrome

Resveratrol Improves Brain-Gut Axis by Regulation of 5-HT-Dependent Signaling in the Rat Model of Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) is at high risk of co-morbid depression and anxiety, which reduces patients’ quality of life and increases the burden of health care costs. However, the pathophysiological mechanisms responsible for IBS still remain unknown. This study investigated the effects of resve...

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Bibliographic Details
Main Authors: Ying-Cong Yu, Jing Li, Meixi Zhang, Jian-Chun Pan, Ying Yu, Jian-Bo Zhang, Liang Zheng, Jian-min Si, Ying Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
irritable bowel syndrome
chronic acute combining stress
pCREB
BDNF
5-HT
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00030/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00030/full

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