Identification of transforming hepatitis B virus S gene nonsense mutations derived from freely replicative viruses in hepatocellular carcinoma.

Identification of transforming hepatitis B virus S gene nonsense mutations derived from freely replicative viruses in hepatocellular carcinoma.

BACKGROUND & AIMS: The correlation between chronic hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) has been well-established. But the roles of viral factor remain uncertain. Only HBV X gene and nonsense mutations of S gene (C-terminal truncation of HBV surface protein) have...

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Main Authors: Shiu-Feng Huang, Ya-Ting Chen, Wei-Chen Lee, Il-Chi Chang, Yu-Ting Chiu, Yu Chang, Hsiao-Chen Tu, Chiou-Hwa Yuh, Isao Matsuura, Liang-Yu Shih, Ming-Wei Lai, Hong-Dar Isaac Wu, Miin-Fu Chen, Chau-Ting Yeh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3933656?pdf=render

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http://europepmc.org/articles/PMC3933656?pdf=render

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