The transcriptional regulator Rok binds A+T-rich DNA and is involved in repression of a mobile genetic element in Bacillus subtilis.

The rok gene of Bacillus subtilis was identified as a negative regulator of competence development. It also controls expression of several genes not related to competence. We found that Rok binds to extended regions of the B. subtilis genome. These regions are characterized by a high A+T content and...

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Bibliographic Details
Main Authors: Wiep Klaas Smits, Alan D Grossman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2978689?pdf=render