Central sensitization of mechanical nociceptive pathways is associated with a long-lasting increase of pinprick-evoked brain potentials
Intense or sustained nociceptor activation, occurring, for example, after skin injury, can induce central sensitization, i.e. an increased responsiveness of nociceptive neurons in the central nervous system. A hallmark of central sensitization is increased mechanical pinprick sensitivity in the area...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-10-01
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Series: | Frontiers in Human Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnhum.2016.00531/full |