Central sensitization of mechanical nociceptive pathways is associated with a long-lasting increase of pinprick-evoked brain potentials

Intense or sustained nociceptor activation, occurring, for example, after skin injury, can induce central sensitization, i.e. an increased responsiveness of nociceptive neurons in the central nervous system. A hallmark of central sensitization is increased mechanical pinprick sensitivity in the area...

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Bibliographic Details
Main Authors: Emanuel Van Den Broeke, Julien Lambert, Gan Huang, André Mouraux
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Human Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2016.00531/full