Extracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and anti-inflammatory and neurogenic properties

Extracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and anti-inflammatory and neurogenic properties

Grafting of neural stem cells (NSCs) derived from human induced pluripotent stem cells (hiPSCs) has shown promise for brain repair after injury or disease, but safety issues have hindered their clinical application. Employing nano-sized extracellular vesicles (EVs) derived from hiPSC-NSCs appears to...

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Bibliographic Details
Main Authors: Raghavendra Upadhya, Leelavathi N. Madhu, Sahithi Attaluri, Daniel Leite Góes Gitaí, Marisa R Pinson, Maheedhar Kodali, Geetha Shetty, Gabriele Zanirati, Smrithi Kumar, Bing Shuai, Susan T Weintraub, Ashok K. Shetty
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Journal of Extracellular Vesicles
Subjects:
anti-inflammatory effects
extracellular vesicles
human induced pluripotent stem cells
ion-exchange chromatography
micrornas
neurogenic properties
proteomics
Online Access:http://dx.doi.org/10.1080/20013078.2020.1809064

Internet

http://dx.doi.org/10.1080/20013078.2020.1809064

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