Image-based personalization of computational models for predicting response of high-grade glioma to chemoradiation

Abstract High-grade gliomas are an aggressive and invasive malignancy which are susceptible to treatment resistance due to heterogeneity in intratumoral properties such as cell proliferation and density and perfusion. Non-invasive imaging approaches can measure these properties, which can then be us...

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Bibliographic Details
Main Authors: David A. Hormuth, Karine A. Al Feghali, Andrew M. Elliott, Thomas E. Yankeelov, Caroline Chung
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87887-4