Development of a Zebrafish Sepsis Model for High-Throughput Drug Discovery

Abstract Sepsis is a leading cause of death worldwide. Current treatment modalities remain largely supportive. Intervention strategies focused on inhibiting specific mediators of the inflammatory host response have been largely unsuccessful, a consequence of an inadequate understanding of the comple...

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Bibliographic Details
Main Authors: Anju M. Philip, Youdong Wang, Antonio Mauro, Suzan El-Rass, John C. Marshall, Warren L. Lee, Arthur S. Slutsky, Claudia C. dos Santos, Xiao-Yan Wen
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.2119/molmed.2016.00188