Nppb Neurons Are Sensors of Mast Cell-Induced Itch

Summary: Itch is an unpleasant skin sensation that can be triggered by exposure to many chemicals, including those released by mast cells. The natriuretic polypeptide b (Nppb)-expressing class of sensory neurons, when activated, elicits scratching responses in mice, but it is unclear which itch-indu...

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Bibliographic Details
Main Authors: Hans Jürgen Solinski, Mette C. Kriegbaum, Pang-Yen Tseng, Thomas W. Earnest, Xinglong Gu, Arnab Barik, Alexander T. Chesler, Mark A. Hoon
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471930275X