RSC primes the quiescent genome for hypertranscription upon cell-cycle re-entry

Quiescence is a reversible G0 state essential for differentiation, regeneration, stem-cell renewal, and immune cell activation. Necessary for long-term survival, quiescent chromatin is compact, hypoacetylated, and transcriptionally inactive. How transcription activates upon cell-cycle re-entry is un...

Full description

Bibliographic Details
Main Authors: Christine E Cucinotta, Rachel H Dell, Keean CA Braceros, Toshio Tsukiyama
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
RSC
Online Access:https://elifesciences.org/articles/67033