Expression Levels of Thymidylate Synthase, Thymidylate Phosphorylase and Dihydropyrimidine Dehydrogenase in Head and Neck Squamous Cell Carcinoma: Preliminary Study

Introduction Pharyngo-laryngeal tumors classified as T3-4, N0-3, M0, are conventionally treated by mutilating surgery (total (pharyngo)-laryngectomy). Neo-adjuvant chemotherapy with 5-FU/platinum salt can be proposed in an attempt to preserve the larynx. The level of the response to chemotherapy ran...

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Bibliographic Details
Main Authors: K. Aubry, J.L. Labourey, J.P. Bessède, N. Tubiana-Mathieu, M. Rigaud
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Clinical Medicine Insights: Oncology
Online Access:https://doi.org/10.1177/117955490800200101