An Improved Synthesis of Some 5-Substituted Indolizines Using Regiospecific Lithiation

An Improved Synthesis of Some 5-Substituted Indolizines Using Regiospecific Lithiation

Various 2-substituted indolizines can be directly and selectively lithiated in the 5 position and subsequent reactions with different electrophiles lead to some novel classes of indolizines. In particular, previously unknown 5-formyl- and 5-iodoindolizine have been prepared by this way and the molec...

Full description

Bibliographic Details
Main Authors: Eugene V. Babaev, Viktor B. Rybakov, Alexander A. Bush, Alexey G. Kuznetsov
Format: Article
Language:English
Published: MDPI AG 2005-09-01
Series:Molecules
Subjects:
Direct lithiation
5-lithiumindolizine
5-formylindolizine
5-iodoindolizine
5-benzoylindolizine
Suzuki reaction
reduction
oxime.
Online Access:http://www.mdpi.com/1420-3049/10/9/1074/

Internet

http://www.mdpi.com/1420-3049/10/9/1074/

Similar Items