Heme Oxygenase Induction Attenuates TNF-α-Induced Hypertension in Pregnant Rodents

Pre-eclampsia is a hypertensive disorder of pregnancy initiated by placental insufficiency and chronic ischemia. In response, several pathways activated in the placenta are responsible for the maternal syndrome, including increased production of the anti-angiogenic protein, sFlt-1, and inflammatory...

Full description

Bibliographic Details
Main Authors: Eric M George, Jacob M Stout, David E Stec, Joey P Granger
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00165/full