Genetic diversity and natural selection of Plasmodium vivax multi-drug resistant gene (pvmdr1) in Mesoamerica

Abstract Background The Plasmodium vivax multidrug resistant 1 gene (pvmdr1) codes for a transmembrane protein of the parasite’s digestive vacuole. It is likely that the pvmdr1 gene mutations occur at different sites by convergent evolution. In here, the genetic variation of pvmdr1 at three sites of...

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Bibliographic Details
Main Authors: Lilia González-Cerón, Alberto Montoya, Josselin C. Corzo-Gómez, Rene Cerritos, Frida Santillán, Marco A. Sandoval
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Malaria Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12936-017-1905-x