Glycyrol suppresses collagen-induced arthritis by regulating autoimmune and inflammatory responses.

Glycyrol is a natural compound extracted from Glycyrrhiza uralensis, first reported by us to be a new immunosuppressant. Here, we demonstrate its beneficial effect in collagen-induced arthritis (CIA) in mice, a model for rheumatoid arthritis (RA) in man, and we document the underlying mechanisms. Pe...

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Bibliographic Details
Main Authors: Yanxia Fu, Hailing Zhou, Shuangyan Wang, Qun Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4103760?pdf=render