A three-hybrid system to probe in vivo protein-protein interactions: application to the essential proteins of the RD1 complex of M. tuberculosis.

BACKGROUND: Protein-protein interactions play a crucial role in enabling a pathogen to survive within a host. In many cases the interactions involve a complex of proteins rather than just two given proteins. This is especially true for pathogens like M. tuberculosis that are able to successfully sur...

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Bibliographic Details
Main Authors: Megha Tharad, Sachin Kumar Samuchiwal, Kuhulika Bhalla, Anamika Ghosh, Krishan Kumar, Sushil Kumar, Anand Ranganathan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3210800?pdf=render