Schistosomal Lipids Activate Human Eosinophils via Toll-Like Receptor 2 and PGD2 Receptors: 15-LO Role in Cytokine Secretion

Schistosomal Lipids Activate Human Eosinophils via Toll-Like Receptor 2 and PGD2 Receptors: 15-LO Role in Cytokine Secretion

Parasite-derived lipids may play important roles in host-pathogen interactions and immune evasion mechanisms. Remarkable accumulation of eosinophils is a characteristic feature of inflammation associated with parasitic disease, especially caused by helminthes. Infiltrating eosinophils are implicated...

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Bibliographic Details
Main Authors: Kelly G. Magalhães, Tatiana Luna-Gomes, Fabio Mesquita-Santos, Rafael Corrêa, Leonardo Santos Assunção, Georgia Correa Atella, Peter F. Weller, Christianne Bandeira-Melo, Patricia T. Bozza
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
eosinophil
PGD2
lipids
schistosoma
TLR
LPC
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03161/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.03161/full

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