Valproic Acid-Mediated Reduction of DNA Double-Strand Break Reparation Capacity of Irradiated MCF-7 Cells

Introduction H istone deacetylase inhibitors (HDIs), as  radiation sensitizing agents, are considered as a novel class of anti-cancer factors, which are studied in various tumor cell-lines. Valproic acid (VPA) is an HDI, which is effectively used in the treatment of epilepsy, migraines, and some par...

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Bibliographic Details
Main Authors: Ahmad yarmohamadi, Jahanbakhsh Asadi, Alireza Khoshbin khoshnazar, Mohammad Mostakhdem Hashemi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-12-01
Series:Iranian Journal of Medical Physics
Subjects:
Online Access:http://ijmp.mums.ac.ir/article_8454_fc8c4cac7fd4f059eb6243dec9a9c44f.pdf