Aquaporin-11 Contributes to TGF-β1-Induced Endoplasmic Reticulum Stress in Human Visceral Adipocytes: Role in Obesity-Associated Inflammation

Aquaporin-11 Contributes to TGF-β1-Induced Endoplasmic Reticulum Stress in Human Visceral Adipocytes: Role in Obesity-Associated Inflammation

Aquaporin-11 (AQP11) is expressed in human adipocytes, but its functional role remains unknown. Since AQP11 is an endoplasmic reticulum (ER)-resident protein that transports water, glycerol, and hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), we hypothesized that this superaq...

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Bibliographic Details
Main Authors: Gema Frühbeck, Inmaculada Balaguer, Leire Méndez-Giménez, Víctor Valentí, Sara Becerril, Victoria Catalán, Javier Gómez-Ambrosi, Camilo Silva, Javier Salvador, Giuseppe Calamita, María M. Malagón, Amaia Rodríguez
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
aquaporins
obesity
endoplasmic reticulum stress
Online Access:https://www.mdpi.com/2073-4409/9/6/1403

Internet

https://www.mdpi.com/2073-4409/9/6/1403

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