Protective role of 1,25(OH)<sub>2</sub>vitamin D<sub>3</sub> in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice

Protective role of 1,25(OH)<sub>2</sub>vitamin D<sub>3</sub> in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice

<p>Abstract</p> <p>Background</p> <p>Intestinal hyper-permeability plays a critical role in the etiopathogenesis of inflammatory bowel disease (IBD) by affecting the penetration of pathogens, toxic compounds and macromolecules. 1,25-dihydroxyvitamin D<sub>3</su...

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Bibliographic Details
Main Authors: Zhao Hongwei, Zhang Hong, Wu Hui, Li Hui, Liu Lei, Guo Jian, Li Chenyang, Shih David Q, Zhang Xiaolan
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Gastroenterology
Subjects:
Barrier protection function
Dextran sulfate sodium
Inflammatory bowel disease
Tight junction
1,25-dihydroxyvitamin D<sub>3</sub>
Online Access:http://www.biomedcentral.com/1471-230X/12/57

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http://www.biomedcentral.com/1471-230X/12/57

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