Macrophages: friend or foe in idiopathic pulmonary fibrosis?

Macrophages: friend or foe in idiopathic pulmonary fibrosis?

Abstract Idiopathic pulmonary fibrosis (IPF) is a prototype of lethal, chronic, progressive interstitial lung disease of unknown etiology. Over the past decade, macrophage has been recognized to play a significant role in IPF pathogenesis. Depending on the local microenvironments, macrophages can be...

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Bibliographic Details
Main Authors: Lei Zhang, Yi Wang, Guorao Wu, Weining Xiong, Weikuan Gu, Cong-Yi Wang
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Respiratory Research
Subjects:
IPF
Macrophage polarization
Classically activated (M1) macrophages
Alternatively activated (M2) macrophages
Therapeutic strategies
Online Access:http://link.springer.com/article/10.1186/s12931-018-0864-2

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http://link.springer.com/article/10.1186/s12931-018-0864-2

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