The evidence for increased L1 activity in the site of human adult brain neurogenesis.

Retroelement activity is a common source of polymorphisms in human genome. The mechanism whereby retroelements contribute to the intraindividual genetic heterogeneity by inserting into the DNA of somatic cells is gaining increasing attention. Brain tissues are suspected to accumulate genetic heterog...

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Bibliographic Details
Main Authors: Alexey A Kurnosov, Svetlana V Ustyugova, Vadim I Nazarov, Anastasia A Minervina, Alexander Yu Komkov, Mikhail Shugay, Mikhail V Pogorelyy, Konstantin V Khodosevich, Ilgar Z Mamedov, Yuri B Lebedev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4331437?pdf=render