Angiotensin II reduces membranous angiotensin-converting enzyme 2 in pressurized human aortic endothelial cells

Introduction. We applied pressure stress to human aortic endothelial cells (HAEC) and investigated whether mechanical pressure stress and/or angiotensin II (Ang II) affected angiotensin-converting enzyme (ACE) 2. We then tested whether the administration of nifedipine had a demonstrable and possibly...

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Bibliographic Details
Main Authors: Kenji Iizuka, Asami Kusunoki, Takuji Machida, Masahiko Hirafuji
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2009-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320309343710