Cation diffusion facilitators transport initiation and regulation is mediated by cation induced conformational changes of the cytoplasmic domain.

Cation diffusion facilitators (CDF) are part of a highly conserved protein family that maintains cellular divalent cation homeostasis in all domains of life. CDF's were shown to be involved in several human diseases, such as Type-II diabetes and neurodegenerative diseases. In this work, we empl...

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Main Authors: Natalie Zeytuni, René Uebe, Michal Maes, Geula Davidov, Michal Baram, Oliver Raschdorf, Merav Nadav-Tsubery, Sofiya Kolusheva, Ronit Bitton, Gil Goobes, Assaf Friedler, Yifat Miller, Dirk Schüler, Raz Zarivach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3962391?pdf=render