Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines

Abstract Background Proper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for pubertal onset and reproduction. To further our understanding of the molecular events taking place during embryonic development, leading to expression of the glycoproteins lutei...

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Bibliographic Details
Main Authors: Huimin Xie, Hanne M. Hoffmann, Anita K. Iyer, Melissa J. Brayman, Cindy Ngo, Mary Jean Sunshine, Pamela L. Mellon
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12958-017-0304-z