HPV Oncoproteins and the Ubiquitin Proteasome System: A Signature of Malignancy?

HPV Oncoproteins and the Ubiquitin Proteasome System: A Signature of Malignancy?

Human papillomavirus (HPV) E6 and E7 oncoproteins are critical for development and maintenance of the malignant phenotype in HPV-induced cancers. These two viral oncoproteins interfere with a plethora of cellular pathways, including the regulation of cell cycle and the control of apoptosis, which ar...

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Bibliographic Details
Main Authors: Anamaria Đukić, Lucija Lulić, Miranda Thomas, Josipa Skelin, Nathaniel Edward Bennett Saidu, Magdalena Grce, Lawrence Banks, Vjekoslav Tomaić
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pathogens
Subjects:
e6
e7
hpv
cervical cancer
proteasome
ups
ubiquitin ligases
ubiquitin
Online Access:https://www.mdpi.com/2076-0817/9/2/133

Internet

https://www.mdpi.com/2076-0817/9/2/133

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