BRCA and early events in the development of high grade serous ovarian cancer

Women who have an inherited mutation in the BRCA1 or BRCA2 genes have a substantial increased lifetime risk of developing epithelial ovarian cancer, and epidemiological factors related to parity, ovulation and hormone regulation have a dramatic effect on the risk in both BRCA mutation carriers and n...

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Bibliographic Details
Main Authors: Sophia HL George, Patricia eShaw
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00005/full