Inflammatory micro-environmental cues of human atherothrombotic arteries confer to vascular smooth muscle cells the capacity to trigger lymphoid neogenesis.

Inflammatory micro-environmental cues of human atherothrombotic arteries confer to vascular smooth muscle cells the capacity to trigger lymphoid neogenesis.

BACKGROUND: Experimental atherosclerosis is characterized by the formation of tertiary lymphoid structures (TLOs) within the adventitial layer, which involves the chemokine-expressing aortic smooth muscle cells (SMCs). TLOs have also been described around human atherothrombotic arteries but the mech...

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Bibliographic Details
Main Authors: Kevin Guedj, Jamila Khallou-Laschet, Marc Clement, Marion Morvan, Sandrine Delbosc, Anh-Thu Gaston, Francesco Andreata, Yves Castier, Catherine Deschildre, Jean-Baptiste Michel, Giuseppina Caligiuri, Antonino Nicoletti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4280229?pdf=render

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http://europepmc.org/articles/PMC4280229?pdf=render

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