NGF-induced cell differentiation and gene activation is mediated by integrative nuclear FGFR1 signaling (INFS).

NGF-induced cell differentiation and gene activation is mediated by integrative nuclear FGFR1 signaling (INFS).

Nerve growth factor (NGF) is the founding member of the polypeptide neurotrophin family responsible for neuronal differentiation. To determine whether the effects of NGF rely upon novel Integrative Nuclear FGF Receptor-1 (FGFR1) Signaling (INFS) we utilized the PC12 clonal cell line, a long-standing...

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Bibliographic Details
Main Authors: Yu-Wei Lee, Ewa K Stachowiak, Barbara Birkaya, Christopher Terranova, Mariolina Capacchietti, Peter Claus, John M Aletta, Michal K Stachowiak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3707895?pdf=render

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http://europepmc.org/articles/PMC3707895?pdf=render

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