Voltage-Dependent Inhibition of Glycine Receptor Channels by Niflumic Acid

Niflumic acid (NFA) is a member of the fenamate class of nonsteroidal anti-inflammatory drugs. This compound and its derivatives are used worldwide clinically for the relief of chronic and acute pain. NFA is also a commonly used blocker of voltage-gated chloride channels. Here we present evidence th...

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Bibliographic Details
Main Authors: Galyna Maleeva, Franck Peiretti, Boris S. Zhorov, Piotr Bregestovski
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00125/full