Using equivalence class counts for fast and accurate testing of differential transcript usage [version 2; peer review: 1 approved, 2 approved with reservations]
Background: RNA sequencing has enabled high-throughput and fine-grained quantitative analyses of the transcriptome. While differential gene expression is the most widely used application of this technology, RNA-seq data also has the resolution to infer differential transcript usage (DTU), which can...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2019-04-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/8-265/v2 |