Using equivalence class counts for fast and accurate testing of differential transcript usage [version 2; peer review: 1 approved, 2 approved with reservations]

Background: RNA sequencing has enabled high-throughput and fine-grained quantitative analyses of the transcriptome. While differential gene expression is the most widely used application of this technology, RNA-seq data also has the resolution to infer differential transcript usage (DTU), which can...

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Bibliographic Details
Main Authors: Marek Cmero, Nadia M. Davidson, Alicia Oshlack
Format: Article
Language:English
Published: F1000 Research Ltd 2019-04-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-265/v2