Pkd1 and Pkd2 are required for normal placental development.

Pkd1 and Pkd2 are required for normal placental development.

Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of inherited renal failure that results from mutations in PKD1 and PKD2. The disorder is characterized by focal cyst formation that involves somatic mutation of the wild type allele in a large fraction of cysts. Consistent with a...

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Bibliographic Details
Main Authors: Miguel A Garcia-Gonzalez, Patricia Outeda, Qin Zhou, Fang Zhou, Luis F Menezes, Feng Qian, David L Huso, Gregory G Germino, Klaus B Piontek, Terry Watnick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2940908?pdf=render

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http://europepmc.org/articles/PMC2940908?pdf=render

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