Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysis

Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysis

Abstract Background Gastric cancers frequently overexpress the epidermal growth factor receptor (EGFR), which has been implicated in pathological processes including tumor cell motility, invasion and metastasis. Targeting EGFR with the inhibitory antibody cetuximab may affect the motile and invasive...

Full description

Bibliographic Details
Main Authors: Simone Keller, Julia Kneissl, Verena Grabher-Meier, Stefan Heindl, Jan Hasenauer, Dieter Maier, Julian Mattes, Peter Winter, Birgit Luber
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Cancer
Subjects:
EGFR
Cetuximab
Motility
Invasion
Gastric cancer
Online Access:http://link.springer.com/article/10.1186/s12885-017-3822-3

Internet

http://link.springer.com/article/10.1186/s12885-017-3822-3

Similar Items