Adipose Lipocalin 2 overexpression protects against age-related decline in thermogenic function of adipose tissue and metabolic deterioration

Objectives: Aging increases the risk for development of adipose tissue dysfunction, insulin resistance, dyslipidemia, and liver steatosis. Lipocalin 2 (Lcn2) deficient mice are more prone to diet-induced obesity and metabolic dysfunction, indicating a protective role for Lcn2 in younger mice. In thi...

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Bibliographic Details
Main Authors: Jessica A. Deis, Hong Guo, Yingjie Wu, Chengyu Liu, David A. Bernlohr, Xiaoli Chen
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819301462