Synthesis, Structure and In Vitro Anti-Trypanosomal Activity of Non-Toxic Arylpyrrole-Based Chalcone Derivatives

Synthesis, Structure and In Vitro Anti-Trypanosomal Activity of Non-Toxic Arylpyrrole-Based Chalcone Derivatives

With an intention of identifying chalcone derivatives exhibiting anti-protozoal activity, a cohort of relatively unexplored arylpyrrole-based chalcone derivatives were synthesized in moderate to good yields. The resultant compounds were evaluated in vitro for their potential activity against a cultu...

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Bibliographic Details
Main Authors: Ayanda I. Zulu, Ogunyemi O. Oderinlo, Cuan Kruger, Michelle Isaacs, Heinrich C. Hoppe, Vincent J. Smith, Clinton G. L. Veale, Setshaba D. Khanye
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
arylpyrrole
chalcones
trypanosomiasis
<i>Trypanosoma brucei</i>
molecular hybridization
Online Access:https://www.mdpi.com/1420-3049/25/7/1668

Internet

https://www.mdpi.com/1420-3049/25/7/1668

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