Probing the coordination and function of Fe4S4 modules in nitrogenase assembly protein NifB

NifB is a key enzyme in the biosynthesis pathway of the nitrogenase FeMo cofactor. Here, the authors investigate the maturation of its iron-sulfur clusters by EPR and biochemical analyses, showing how individual precursor clusters participate in the formation of the final iron-sulfur cluster.

Bibliographic Details
Main Authors: Lee A. Rettberg, Jarett Wilcoxen, Chi Chung Lee, Martin T. Stiebritz, Kazuki Tanifuji, R. David Britt, Yilin Hu
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05272-8