Comparison of an in-house 'home-brew' and commercial ViroSeq integrase genotyping assays on HIV-1 subtype C samples.

Comparison of an in-house 'home-brew' and commercial ViroSeq integrase genotyping assays on HIV-1 subtype C samples.

<h4>Background</h4>Roll-out of Integrase Strand Transfer Inhibitors (INSTIs) such as dolutegravir for HIV combination antiretroviral therapy (cART) in sub-Saharan Africa necessitates the development of affordable HIV drug resistance (HIVDR) assays targeting the Integrase gene. We optimis...

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Bibliographic Details
Main Authors: Kaelo K Seatla, Wonderful T Choga, Mompati Mogwele, Thabo Diphoko, Dorcas Maruapula, Lucy Mupfumi, Rosemary M Musonda, Christopher F Rowley, Ava Avalos, Ishmael Kasvosve, Sikhulile Moyo, Simani Gaseitsiwe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224292

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https://doi.org/10.1371/journal.pone.0224292

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