Association of severe malaria outcomes with platelet-mediated clumping and adhesion to a novel host receptor.

<h4>Introduction</h4>Severe malaria has been attributed partly to the sequestration of Plasmodium falciparum-infected erythrocytes (IEs) in the microvasculature of vital host organs. Identification of P. falciparum cytoadherence phenotypes that are associated with severe malaria may lead...

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Main Authors: Alfredo Mayor, Abdul Hafiz, Quique Bassat, Eduard Rovira-Vallbona, Sergi Sanz, Sónia Machevo, Ruth Aguilar, Pau Cisteró, Betuel Sigaúque, Clara Menéndez, Pedro L Alonso, Chetan E Chitnis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21559373/pdf/?tool=EBI