Tau: A Signaling Hub Protein

Over four decades ago, in vitro experiments showed that tau protein interacts with and stabilizes microtubules in a phosphorylation-dependent manner. This observation fueled the widespread hypotheses that these properties extend to living neurons and that reduced stability of microtubules represents...

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Bibliographic Details
Main Authors: Rebecca L. Mueller, Benjamin Combs, Mohammed M. Alhadidy, Scott T. Brady, Gerardo A. Morfini, Nicholas M. Kanaan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.647054/full