Increased oxidative damage in peripheral blood correlates with severity of Parkinson's disease

Increased oxidative damage in peripheral blood correlates with severity of Parkinson's disease

Increased oxidative stress contributes to neuronal dysfunction in Parkinson's disease (PD). We investigated whether the pathological changes in PD brains may also be present in peripheral tissues. Leukocyte 8-hydroxydeoxyguanosine (8-OHdG), plasma malondialdehyde (MDA), erythrocyte glutathione...

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Bibliographic Details
Main Authors: Chiung-Mei Chen, Jun-Liang Liu, Yih-Ru Wu, Yi-Chun Chen, Huey-Shinn Cheng, Mei-Ling Cheng, Daniel Tsun-yee Chiu
Format: Article
Language:English
Published: Elsevier 2009-03-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Oxidative stress
Peripheral blood
Disease severity
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108003008

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http://www.sciencedirect.com/science/article/pii/S0969996108003008

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