Adenosine deaminase 2 activity negatively correlates with age during childhood

Abstract Background Human adenosine deaminase 2 (ADA2) is an extracellular enzyme that negatively regulates adenosine-mediated cell signaling by converting adenosine to inosine. Altered ADA2 enzyme activity has been associated with some viral infections and rheumatic diseases. The potential utility...

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Bibliographic Details
Main Authors: Sarah M. Bowers, Kristen M. Gibson, David A. Cabral, Kelly L. Brown
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Pediatric Rheumatology Online Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12969-020-00446-5